Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency

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Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency.

BACKGROUND Ascorbate and glutathione play central roles in the defense against free radicals and oxidants that are implicated in chronic diseases. OBJECTIVE The objective was to determine the ability of vitamin C supplements to modulate the concentration of glutathione in human lymphocytes. DESIGN The effect of vitamin C supplements was determined in a sequential study with time points befo...

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Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency1–3

Background: Ascorbate and glutathione play central roles in the defense against free radicals and oxidants that are implicated in chronic diseases. Objective: The objective was to determine the ability of vitamin C supplements to modulate the concentration of glutathione in human lymphocytes. Design: The effect of vitamin C supplements was determined in a sequential study with time points befor...

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Vitamin D Deficiency is Associated with the Metabolic Syndrome in Subjects with Type 2 Diabetes

Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...

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In order to study the interaction of glutathione, vitamin C and vitamin E under hyperoxia (95 % oxygen) and hyperbaric oxygen (2.5 atmospheric pressure), 20 days old male Guinea pigs were fed with basal vitamin C free diet, while receiving a vitamin C supplement of either high concentration (50 mg/day) or low concentration (1 mg/day) for two weeks. Animals were than exposed to hyperoxia and hyp...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2003

ISSN: 0002-9165,1938-3207

DOI: 10.1093/ajcn/77.1.189